National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-11547-f

Testing Status of Triprolidine - 11547-F

 

CASRN: 486-12-4

Formula: C19-H22-N2

Synonyms/Common Names

  • Tripyrolidine

Known Uses

Antihistamine

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C61450)  Completed 
    • NR-414/415  (Peer Review Approval NA)
      Triprolidine: 104 Week Chronic Dose Study in Rats and Triprolidine: 104 Week Chronic Dose Study in Mice (Contact CDM@niehs.nih.gov for an electronic copy of this report)
    • Rats: F344/N; Mice: B6C3F1
  • 13-Week (Dosed-Feed)  (C61450)  Completed 
    • NR-414/415
      Triprolidine: 104 Week Chronic Dose Study in Rats and Triprolidine: 104 Week Chronic Dose Study in Mice (Contact CDM@niehs.nih.gov for an electronic copy of this report)
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, 250, 4000 PPM.

Long-Term Carcinogenicity

  • 2 years (Dosed-Feed)  (C61450)  Report Complete 
    • NR-414/415  (Peer Review Approval NA)
      Triprolidine: 104 Week Chronic Dose Study in Rats and Triprolidine: 104 Week Chronic Dose Study in Mice (Contact CDM@niehs.nih.gov for an electronic copy of this report)
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R: 0, 250, 1000, 2000, M: 0, 500, 2000, 4000 PPM.
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