Testing Status of 9-Aminoacridine, monohydrochloride, monohydrate 11550-K

 

CASRN: 52417-22-8

Formula: C13-H10-N2.Cl-H.H2-O

Synonyms/Common Names

  • 9-Acridamine, monohydrochloride, monohydrate

Known Uses

Germicide, fungicide

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Toxicokinetic Study (Gavage; Intravenous)  (S0251)  Completed 
    • Male Rats: F344/N

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (686905)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Positive 
  • Drosophila  (331579)  Completed 
    • Citation: Yoon, J.S., Mason, J.M., Valencia, R., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: IV. Results of 45 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 349-367
    • Reciprocal Translocation/Sex-Linked Recessive Lethal Negative 
  • Drosophila  (745093)  Completed 
    • Citation: Valencia, R., Mason, J.M., and Zimmering, S. Chemical mutagenesis testing in Drosophila. IV. Interlaboratory comparison of mutagenicity tests after treatment of larvae. Environ. Molec. Mutagen. Vol. 14 (1989) 238-244
    • Sex-Linked Recessive Lethal Positive 
    • Reciprocal Translocation Negative 
  • Drosophila  (824241)  Completed 
    • Citation: Valencia, R., Mason, J.M., and Zimmering, S. Chemical mutagenesis testing in Drosophila. IV. Interlaboratory comparison of mutagenicity tests after treatment of larvae. Environ. Molec. Mutagen. Vol. 14 (1989) 238-244
    • Reciprocal Translocation/Sex-Linked Recessive Lethal Negative 
  • Salmonella  (420206)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Positive 
  • Salmonella  (493413)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Positive 
  • Salmonella  (874511)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Positive