Testing Status of Barium chloride dihydrate 11611-N

 

CASRN: 10326-27-9

Formula: Ba-Cl2.2H2-O

Synonyms/Common Names

  • Barium chloride dihydrate

Known Uses

Chemical reagent. Boiler compounds. Pigments and textile dyeing. As a pesticide, and in medicine as a cardiac stimulant.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14-Day (Dosed-Water)  (C61074A)  Completed 
    • Rats: F344/N; Mice: B6C3F1
  • 13-Week (Dosed-Water)  (C61074A)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, 125, 4000 PPM/10 PER GROUP.

Long-Term Carcinogenicity

  • 2 years (Dosed-Water)  (C61074B)  Report Complete 
    • TR-432 (NIH Number: 94-3163)  (Peer Review Approval 06/22/1993A )
      Toxicology and Carcinogenesis Studies of Barium Chloride Dihydrate (CASRN 10326-27-9) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)
    • Rats: F344/N; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats No Evidence 
      • Female Rats No Evidence 
      • Male Mice No Evidence 
      • Female Mice No Evidence 
    • Dose: 0, 500, 1200, 2500 PPM.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (384673)  Completed 
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Mouse Lymphoma  (741714)  Completed 
    • Mice
    •  Positive 
  • Salmonella  (007321)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Negative 

Organ Systems Toxicity

  • Neurotoxicology Assessment (Dosed-Feed)  (NTA94032)  Completed 
    • Citation: Animal Neurobehavioral Test Battery in NTP Assessment In: Advances in Neurobehavioral Toxicology: Applications in Environmental & Occupational Health (Barry L. Johnson, ED.), Lewis Publishers, Inc. pp. 403-418 (1990).
    • Male and Female Rats/Mice: F344/N