National Toxicology Program

National Toxicology Program

Testing Status of Curcumin - 11612-S


CASRN: 458-37-7

Related: TUMERIC, OLEORESIN (10105-J)

Formula: C21-H20-O6

Synonyms/Common Names

  • 1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
  • C.I. Natural Yellow 3
  • Curcuma
  • Diferuloylmethane
  • Indian saffron
  • Merita earth
  • Souchet
  • Yellow ginger
  • Yellow root

Known Uses

Dyeing cotton, wool, silk; coloring oils & waxes; boron indicator; stain in microscopy; alkali indicator; preparing curcuma paper; food dye; analytical agent.

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Micronucleus  (A43540)  Completed 
    • Rats: Fischer 344
    • Male Negative 
  • Salmonella  (489345)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Negative 
  • Salmonella  (A73195)  Completed 
    •  Negative 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.