Testing Status of Phenolic Benzotriazoles (Drometrizole) 12010

 

CASRN: 2440-22-4

Formula: C13-H11-N3-O

Synonyms/Common Names

  • Drometrizol
  • PBZT

Secondary:

  • BENZOTRIAZOLES - Phenolic Benzotriazoles

Known Uses

UV absorber; Ultraviolet screen; Plastic additive from polymethyl methacrylate; EPA Pesticide Inert Ingredient

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14 days (Gavage)  (C12010)  On Test 
    • Benzotriazole Class
    • Rats: Harlan Sprague-Dawley
    • Dose: Male rats: 0, 30, 100, 300, or 1000 mg/kg in 0.5% aqueous methylcellulose.

Special Studies

  • Toxicokinetic Study (Gavage; Intravenous)  (K12010)  On Test 
    • Male Rats: Harlan Sprague-Dawley
    • Dose: 30 mg/kg. 30, 300 mg/kg.

Genetic Toxicology

  • Micronucleus  (G12010)  On Test 
    • Rats: Harlan Sprague-Dawley