National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-12013

Testing Status of Phenolic Benzotriazoles (2-(5-Chloro-2H-benzotriazol-2-yl)-4,6-bis(1,1-dimethylethyl)phenol) - 12013

 

CASRN: 3864-99-1

Formula: C20-H24-Cl-N3-O

Synonyms/Common Names

  • 2,4-Di-tert-butyl-6-(5-chlorobenzotriazol-2-yl)phenol
  • PBZT

Secondary:

  • BENZOTRIAZOLES - Phenolic Benzotriazoles

Known Uses

UV stabilizer

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14 days (Gavage)  (C12013)  On Test 
    • Benzotriazole Class
    • Rats: Harlan Sprague-Dawley
    • Dose: MR: 0, 30, 100, 300, or 1000 mg/kg in 0.5% aqueous methylcellulose by gavage.

Special Studies

  • Toxicokinetic Study (Gavage)  (K12013)  On Test 
    • Male Rats: Harlan Sprague-Dawley
  • Toxicokinetic Study (Intravenous)  (K12013)  On Test 
    • Male Rats: Harlan Sprague-Dawley

Genetic Toxicology

  • Micronucleus  (G12013)  On Test 
    • Rats: Harlan Sprague-Dawley
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.