National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-13111

Testing Status of Phenolic Benzotriazoles (2-(2H-Benzotriazol-2-yl)phenol) - 13111

 

CASRN: 10096-91-0

Formula: C12-H9-N3-O

Synonyms/Common Names

  • PBZT
  • Phenolic Benzotriazole

Secondary:

  • BENZOTRIAZOLES - Phenolic Benzotriazoles

Known Uses

Used as UV stabilizer and as industrial additives: paints and coatings, rubber and plastic products, and electrical and electronic products, but some are used in food, contact polymers and adhesives, cosmetics, sunscreens, and fragrances.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14 days (Gavage)  (C13111)  On Test 
    • Benzotriazole Class
    • Rats: Harlan Sprague-Dawley
    • Dose: MR: 0, 30, 100, 300, or 1000 mg/kg in 0.5% aqueous methylcellulose by gavage.

Special Studies

  • Toxicokinetic Study (Gavage; Intravenous)  (K13111)  On Test 
    • Male Rats: Harlan Sprague-Dawley

Genetic Toxicology

  • Micronucleus  (G13111)  On Test 
    • Rats: Harlan Sprague-Dawley
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.