National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-13114

Testing Status of Phenolic Benzotriazoles (2-(2H-Benzotriazol-2-yl)-4-tert-butylphenol) - 13114

 

CASRN: 3147-76-0

Formula: C16-H17-N3-O

Synonyms/Common Names

  • PBZT
  • tBu-BZT

Secondary:

  • BENZOTRIAZOLES - Phenolic Benzotriazoles

Known Uses

Phenolic benzotriazoles are a class of ultraviolet-light absorbers. Compounds within this class are used in a variety of consumer applications including in polymers and sunscreens.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14 days (Gavage)  (C13114)  On Test 
    • Benzotriazole Class
    • Rats: Harlan Sprague-Dawley
    • Dose: MR: 0, 30, 100, 300, or 1000 mg/kg in 0.5% aqueous methylcellulose.

Special Studies

  • Toxicokinetic Study (Gavage; Intravenous)  (K13114)  On Test 
    • Male Rats: Harlan Sprague-Dawley
    • Dose: 30 mg/kg. 30, 300 mg/kg.

Genetic Toxicology

  • Micronucleus  (G13114)  On Test 
    • Rats: Harlan Sprague-Dawley
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