National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-13115

Testing Status of Phenolic Benzotriazoles (3-(2H-Benzotriazol-2-yl)-5-(1,1-dimethylethyl)-4-hydroxybenzenepropanoic acid, octyl ester) - 13115

 

CASRN: 84268-23-5

Synonyms/Common Names

  • PBZT

Secondary:

  • BENZOTRIAZOLES - Phenolic Benzotriazoles

Known Uses

Phenolic benzotriazoles are a class of ultraviolet-light absorbers. Compounds within this class are used in a variety of consumer applications including polymers and sunscreens.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14 days (Gavage)  (C13115)  On Test 
    • Benzotriazole Class
    • Rats: Harlan Sprague-Dawley
    • Dose: MR: 0, 30, 100, 300, or 1000 mg/kg in 0.5% aqueous methylcellulose by gavage.

Special Studies

  • Toxicokinetic Study (Gavage; Intravenous)  (K13115)  On Test 
    • Male Rats: Harlan Sprague-Dawley

Genetic Toxicology

  • Micronucleus  (G13115)  On Test 
    • Rats: Harlan Sprague-Dawley
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.