National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-14011

Testing Status of Propylene glycol phenyl ether - 14011

 

CASRN: 770-35-4

Formula: C9-H12-O2

Synonyms/Common Names

  • PPh

Known Uses

PPh is used as a solvent and coalescing agent. PPh is formulated into architectural and industrial coatings, electrodeposition coatings, textile dyes, textile printing pastes, paint removers, latex adhesives and inks for ball-point pens, felt-tip pens, and stamp pads.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 5 days (Gavage)  (C14011)  Completed 
    • Rats: Harlan Sprague-Dawley
    • Dose: MR: 0, 10, 100, 500, 1000, or 2000 mg/kg; 8 rats in 0 mg/kg group, 6 rats in each treated group.

Special Studies

  • C. elegans  (W14011)  Completed 
    • C. elegans: N2

Genetic Toxicology

  • Micronucleus  (G14011)  Completed 
    • Rats: Harlan Sprague-Dawley
    • Male Negative 
  • Salmonella  (G14011B)  Completed 
    •  Negative 

Toxicogenomics

  • Microarray Analysis (Gavage)  (T14011)  Completed 
    • Short Term Toxicogenomic Studies
    • Rats: Harlan Sprague-Dawley

Other

  • Zebrafish Developmental Selected
  • High Throughput Screening Selected
  • Structure Activity Relationship (SAR) Analysis Selected
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.