Testing Status of Aloin 15037
Related: Aloin A
Aloin, a natural mixed diastereomer (A/B) anthracycline from aloe plant, may be studied as a chemopreventive factor and antineoplastic agent. Aloin inhibits angiogenesis, enhances melanogenesis and regulates transglutaminase activity. Aloin may be used to assess its activity as a selective phosphodiesterase inhibitor. Aloin A is used as a stabilizer in the preparation of gold and silver nanoparticles.
- 13 weeks (Dosed-Water)
- Rats: F344 (NCTR)
- Dose: MR: 0, 6.95. 13.9, 27.8, 55.7, 111, 223, or 446 ppm; 10 per/group.