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Testing Status of Echinacea purpurea root extract 16001

 

CASRN: 90028-20-9

Synonyms/Common Names

  • ECH
  • Echinacea purpurea

Known Uses

Herb used for medicinal and cosmetic purposes

Chemical Properties

Toxicity Effects (HSDB)

Modified One-Generation

  • 6 weeks Dose Range Finding (Gavage)  (MOG16001)  On Test 
    • Perinatal Dose Range-Finding MOG Study of Echinacea purpurea extract
    • Female Rats: Harlan Sprague-Dawley
    • Dose: 0, 125, 250, 500, 1000, or 2000 mg/kg/day.
  • 3 weeks Conventional Teratology (Gavage)  (MOG16001B)  On Test 
    • Rats: Harlan Sprague-Dawley
    • Dose: 100, 300, 1000 mg/kg/day by gavage.
  • Fertility Assessment (Gavage)  (MOG16001B)  On Test 
    • Rats: Harlan Sprague-Dawley
    • Dose: 100, 300, 1000 mg/kg/day by gavage.
  • 13 weeks Subchronic (Gavage)  (MOG16001B)  On Test 
    • Rats: Harlan Sprague-Dawley
    • Dose: 100, 300, 1000 mg/kg/day by gavage.

Genetic Toxicology

  • Micronucleus  (G16001B)  On Test 
    • Rats
  • Micronucleus  (G16001)  On Test 
    • Male Rats
    • Rats: Sprague Dawley

Organ Systems Toxicity

  • 28 days Immunotoxicity (Gavage) Selected (I16001)  
    • Female Rats: Harlan Sprague-Dawley
    • Dose: 0, 125, 250, 500, 1000, or 2000 mg/kg.