National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-16011

Testing Status of 2-((1-(4-Phenoxyphenoxy)propan-2-yl)oxy)pyridine - 16011

 

CASRN: 95737-68-1

Related: MPPE

Formula: C20-H19-N-O3

Synonyms/Common Names

  • MPEP
  • MPPE
  • Pyridine, 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]-
  • 2-[1-methyl-2-(4-phenoxyphenoxy)ethoxy]pyridine
  • Pyriproxyfen

Known Uses

Agricultural Chemical, Insecticide Juvenile hormone analog and insect growth regulator used to control insects by disrupting metamorphosis. Has been effective in controlling mosquito larvae.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Preliminary Toxicokinetic Study (Gavage)  (K16011B)  On Test 
    • Female Rabbit
  • GD 6-18 Toxicokinetic Study (Gavage)  (K16011)  On Test 
    • Pilot TK (Pilot Fetal Transfer Study on MPEP)
    • Rats: Harlan Sprague-Dawley
    • Dose: 0, 62.5, 250 mg/kg per day.

Organ Systems Toxicity

  • 28 days Immunotoxicity (Gavage)  (I16011)  On Test 
    • Female Rats: Harlan Sprague-Dawley
    • Dose: 0, 63, 125, 250, or 500 mg/kg/day.
  • Conventional Teratology (Gavage)  (R16011B)  On Test 
    • Rabbit Teratology
    • Female Rabbit: New Zealand White
  • GD 6-21 Conventional Teratology (Gavage)  (R16011)  On Test 
    • Rat Teratology
    • Female Rats: Hsd:Sprague Dawley SD
    • Dose: Rat: 0, 62.5, 125, 250, 500 mg/kg/day.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.