Testing Status of D-Camphor 464493

 

CASRN: 464-49-3

Formula: C10-H16-O

Synonyms/Common Names

  • Bicyclo(2.2.1)heptan-2-one, 1,7,7-trimethyl-

Known Uses

Used in skin ointments as local irritant

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (A44191)  Completed 
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Salmonella  (374268)  Completed 
    •  Negative 

Organ Systems Toxicity

  • Conventional Teratology (Gavage)  (TER91018)  Completed 
    • Citation: Final Report on the Developmental Toxicity of d-Camphor in Sprague-Dawley (CD) Rats
    • Female Rats: Sprague Dawley
    • Rats Maternal Inadequate 
    • Rats Fetal Negative 
    • Dose: 0, 100, 400, 800 MG/KG/DAY.
  • Conventional Teratology (Gavage)  (TER91019)  Completed 
    • Citation: Final Report on the Developmental Toxicity of d-Camphor in New Zealand White Rabbits
    • Female Rabbit: New Zealand White
    • Rabbits Maternal Negative 
    • Rabbits Fetal Negative 
    • Dose: 0, 50, 200, 400 MG/KG/DAY.
  • 6 to 15 GD Teratology Pilot Studies (Gavage)  (TRP90010)  Completed 
    • Female Rats: Sprague Dawley
    • Dose: 0, 100, 500, 800, 1250, OR 2500 MG/KG.
  • 6 to 19 GD Teratology Pilot Studies (Gavage)  (TRP90011)  Completed 
    • Female Rabbit: New Zealand White
    • Dose: 0, 100, 200, 350, OR 500 MG/KG.