National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-4759482

Testing Status of 13-cis-Retinoic acid - 4759482

 

CASRN: 4759-48-2

Formula: C20-H28-O2

Synonyms/Common Names

  • Accutane
  • Isotretinoin
  • Neovitamin A acid
  • Retinoic acid, 13-Cis- (8CI)(9CI)

Known Uses

Medication in treatment of severe cystic acne, vitamin A derivative (Merck 1989)

Chemical Properties

Toxicity Effects (HSDB)

Organ Systems Toxicity

  • 8 to 15 GD (copulatory plug=0 GD) Short-Term in vivo Repro. Tox. (Gavage)  (T0131)  Completed 
    • Female Mice: Swiss
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