Testing Status of 5-Methoxypsoralen 484208

 

CASRN: 484-20-8

Formula: C12-H8-O4

Synonyms/Common Names

  • Bergapten
  • 4-Methoxy-7H-furo(3,2-q)(1)benzopyran-7-one (9CI)

Known Uses

Tanning agent in suntan preparations, antipsoriatic agent (Merck 1989). Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Chromosome Aberrations  (653449)  Completed 
    • Citation: Shelby, M.D. and Witt, K.L. Comparision of Results from Mouse Bone Marrow Chromosome Aberration and Micronucleus Test 25 (1995) Vol. 25, 1995 302-313
    • Mice
    •  Positive 
  • In Vitro Cytogenetics (CA/SCE)  (197424)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Positive 
  • Micronucleus  (241132)  Completed 
    • Citation: Shelby, M.D. and Witt, K.L. Comparision of Results from Mouse Bone Marrow Chromosome Aberration and Micronucleus Test 25 (1995) Vol. 25, 1995 302-313
    • Mice: B6C3F1
    • Male Negative 
  • Salmonella  (110410)  Completed 
    •  Positive