National Toxicology Program

National Toxicology Program

Testing Status of 6-Propyl-2-thiouracil - 51525


CASRN: 51-52-5

Formula: C7-H10-N2-O-S

Synonyms/Common Names

  • Propycil

Known Uses

Thyroid inhibitor

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Genetic Toxicology

  • Salmonella  (958046)  Completed 
    •  Negative 

Organ Systems Toxicity

  • 10 to 20 GD Neurotoxicology Assessment (Dosed-Water)  (NTA99001)  Completed 
    • Male and Female Rats: Long-Evans Hooded
    • Dose: 0, 5, OR 25 PPM.
  • AD libitum for 1st generation Continuous Breeding (Legacy) (Dosed-Water)  (RACB20102)  Completed 
    • Citation: Two-Generation Reproduction Toxicity Study of Propylthiouracil (CAS#51-52-5) when Administered to Sprague-Dawley Rats in the Drinking Water (September 2003)
    • Male and Female Rats: Sprague Dawley
    • Dose: 0, 0.0001%, 0.0004%, OR 0.0015%.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.