Testing Status of Cupric sulfate 7758998

 

CASRN: 7758-99-8

Formula: Cu.H2-O4-S.5H2-O

Synonyms/Common Names

  • Copper sulfate
  • Sulfuric acid copper(2+) salt (1:1), pentahydrate

Known Uses

Preservative. Electroplating. Battery electrolyte. Ore flotation. Photographic toner reagent. Inks. Food and fertilizer additive, topical anti-fungal, occurs in nature as mineral hydrocyanite (Merck 1989)

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 2 weeks (Dosed-Feed)  (C62191B)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R& M: 0, 1000, 2000, 4000, 8000, 16000 PPM (5/S/S).
  • 2 weeks (Dosed-Water)  (C62191)  Completed 
    • Rats: F344/N; Mice: B6C3F1
  • 13 weeks (Dosed-Feed)  (C62191B)  Report Complete 
    • TOX-29 (NIH Number: 93-3352)
      Toxicity Studies of Cupric Sulfate (CASRN 7758-99-8) Administered in Drinking Water and Feed to F344/N Rats and B6C3F1 Mice
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R: 0, 500, 1000, 2000, 4000, 8000 PPM M: 0, 1000, 2000, 4000, 8000, 16000 PPM (10/S/S).

Special Studies

  • C. elegans  (S0948)  Completed 
    • C. elegans

Genetic Toxicology

  • Micronucleus  (A61262)  Completed 
    • Citation: Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
    • Mice: B6C3F1
    • Male Equivocal 
    • Female Negative