National Toxicology Program

National Toxicology Program

Testing Status of Methacrylamide - 79390


CASRN: 79-39-0

Formula: C4-H7-N-O

Synonyms/Common Names

  • 2-Methyl-2-propenamide (9CI)

Known Uses

In manufacture of resins & plastics. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Organ Systems Toxicity

  • Continuous Breeding (Legacy) (Dosed-Water)  (RACB90018)  Completed 
    • Citation: Final Report on the Reproductive Toxicity of Methcrylamide in CD-1 Swiss Mice
    • Male and Female Mice: Swiss
    • Dose: 0,60,180,360,540,720 PPM; 0,24,80,240 PPM; NA; 0,24,80,240 PPM.
  • 6 to 17 GD Conventional Teratology (Gavage)  (TER90007)  Completed 
    • Citation: Final Report on the Developmental Toxicity of Methacrylamide in CD-1 Swiss Mice
    • Female Mice: Swiss
    • Mice Maternal Positive 
    • Mice Fetal Positive 
    • Dose: 30, 60, 120, 180 MG/KG.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.