National Toxicology Program

Testing Status of o-Phenylenediamine - 95545

CASRN: 95-54-5

Formula: C6-H8-N2

Synonyms/Common Names

• 1,2-Benzenediamine (9CI)

Known Uses

Photographic developer. Organic synthesis. Chemical intermediate for dyes, pigments, fungicides. Laboratory reagent. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

• In Vitro Cytogenetics (CA/SCE)  (773292)  Completed 
  • Sister Chromatid Exchange Positive 
  • Chromosome Aberrations Positive 
• Salmonella  (856966)  Completed 
  • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
  •  Positive