National Toxicology Program

National Toxicology Program

Testing Status of Aldrin - C00044


CASRN: 309-00-2

Formula: C12-H8-Cl6

Synonyms/Common Names

  • ENT 15,949

Known Uses

Insecticide. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C00044)  Completed 
    • Rats: Osborne Mendel; Mice: B6C3F1
  • 13-Week (Dosed-Feed)  (C00044)  Completed 
    • Rats: Osborne Mendel; Mice: B6C3F1
    • Dose: R: 0, 40, 320, M: 0, 2.5, 80 PPM/5 PER GROUP.

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C00044)  Report Complete 
    • TR-021 (NIH Number: 78-821)  (Peer Review Approval 09/26/1977A )
      Bioassays of Aldrin and Dieldrin for Possible Carcinogenicity (CASRN 309-00-2) (CASRN 60-57-1)
    • Rats: Osborne Mendel; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Rats Equivocal 
      • Female Rats Equivocal 
      • Male Mice Positive 
      • Female Mice Negative 
    • Dose: R:0, 30, 60 MM:0, 4, 8 FM:0, 3, 6 PPM/50 PER GROUP.

Genetic Toxicology

  • Salmonella  (127997)  Completed 
    • Citation: Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelman, K. Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen. Vol. 19 (Suppl 21) (1992) 2-141
    •  Negative 
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.