National Toxicology Program

National Toxicology Program

Testing Status of 6-Methylmercaptopurine ribonucleoside - C04784


CASRN: 342-69-8

Formula: C11-H14-N4-O4-S

Synonyms/Common Names

  • 6-(Methylthio)-9-beta-D-ribofuranosyl-9H-purine

Known Uses

Chemotherapeutic agent

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 14-Day (Intraperitoneal Injection)  (C04784)  Completed 
    • Rats: Sprague Dawley; Mice: Swiss
  • 13-Week (Intraperitoneal Injection)  (C04784)  Completed 
    • Rats: Sprague Dawley; Mice: Swiss

Long-Term Carcinogenicity

  • 2-Year (Intraperitoneal Injection)  (C04784)  Report Complete 
    •   (Peer Review Approval NA) Citation: EK Weisburger, Bioassay Program for Carcinogenic Hazards of Cancer Chemotherapeutic Agents. Cancer 40:1935-1949 (1977)
    • Rats: Sprague Dawley; Mice: Swiss
    • Dose: R: 0, 2.2, 4.5, 9, M: 0, 10, 20 MG/KG/25 PER GROUP.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.