National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-c60253d

Testing Status of Asbestos, amosite + Dimethyl hydrazine - C60253D

 

CASRN: 12172-73-5

Related: ASBESTOS, AMOSITE

Known Uses

Asbestos, chrysotile: asbestos cement. Textiles. Insulation. Friction products. Fireproofing agent. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 13-Week (Dosed-Feed)  (C60253D)  Completed 
    • Rats: F344/N

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C60253D)  Report Complete 
    • TR-279 (NIH Number: 91-2535)  (Peer Review Approval 09/22/1982A )
      Toxicology and Carcinogenesis Studies of Amosite Asbestos (CASRN 12172-73-5) in F344/N Rats (Feed Studies)
    • Rats: F344/N
    • Carcinogenesis Results
      • Male Rats Inadequate Study 
      • Female Rats Inadequate Study 
    • Dose: 0, 1% /250 PER GROUP.
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