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Testing Status of Casanthranol (cascara sagrada extract) EMTDP79

 

CASRN: 8024-48-4

Formula: N/F

Synonyms/Common Names

  • Casanthranol

Known Uses

Naturally occurring cathartic obtained from the bark of the buckhorn tree

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (A16214)  Completed 
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Micronucleus  (A00989)  Completed 
    • Rats: Fischer 344
    • Male Negative 
  • Micronucleus  (A33602)  Completed 
    • Mice: B6C3F1
    • Male Negative 
  • Salmonella  (357262)  Completed 
    •  Positive