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Testing Status of Transgenic Model Evaluation II (Acesulfame Potassium) M000003

 

CASRN: 55589-62-3

Synonyms/Common Names

  • Acesulfame Potassium Transgenic Model Evaluation II
  • 1,2,3-Oxathiazin-4(3H)-one, 6-methyl-, 2,2-dioxide, potassium salt
  • Sunett

Secondary:

  • TGMODELEVAL - Transgenic model evaluation

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 39 weeks (Dosed-Feed)  (C99039)  Completed 
    • GMM-02 (NIH Number: 06-4460)  (Peer Review Approval 05/22/2003A )
      Toxicity Studies of Acesulfame Potassium (CAS No. 55589-62-3) in FVB/N-TgN(v-Ha-ras)Led (Tg.AC) Hemizygous Mice and Carcinogenicity Studies of Acesulfame Potassium in B6.129-Trp53tm1Brd (N5) Haploinsufficient Mice (Feed Studies)
    • Mice: P53 +/- (C57BL/6); Mice: Tg.AC (FVB/N) Hemizygous
    • Dose: 0, 0.3, 1, OR 3%; 15/SEX/SPECIES/DOSE.