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Testing Status of Kawain M000076


CASRN: 1635-33-2

Formula: C14-H14-O3

Synonyms/Common Names

  • Cavain
  • 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethenyl)-
  • Kavain
  • Kavaine
  • Neuronica

Known Uses

Anti-anxiety agent; anticonvulsant

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Absorption Disposition Metabolism Elimination (Gavage)  (S0915)  Completed 
    • Citation: Final Study Report. Kawain. 10/30/00 - 06/13/05. June 13, 2005.
    • Male Rats: F344/N; Female Mice: B6C3F1
    • Dose: 100 mg/kg kawain, 100 mg/kg kavalactones, 1 g/kg kava extract ; 100 mg/kg kavalactones.