Testing Status of Flutamide M010040

 

CASRN: 13311-84-7

Formula: C11-H11-F3-N2-O3

Synonyms/Common Names

  • Eulexin
  • 2-Methyl-N-[4'-nitro-3'-(trifluoromethyl)phenyl]propanamide
  • M-Propionotoluidide, alpha, alpha, alpha-trifluoro-2-methyl-4'-nitro- (8CI)

Known Uses

antineoplastic (prostatic carcinoma); therapeutic agent; androgen antagonist

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 4 days (Gavage)  (C01040)  Completed 
    • Liver Targeted Testing study of Toxcast Chemicals
    • Rats: Harlan Sprague-Dawley
    • Dose: Male rats: 0, 10 mg/kg/day.

Organ Systems Toxicity

  • Continuous Breeding (Legacy) (Gavage)  (RACB20107B)  Completed 
    • Male and Female Rats: SD & Wistar
    • Dose: 50 MG/KG DAY.

Toxicogenomics

  • 4 days Microarray Analysis (Gavage)  (T01040)  Completed 
    • Liver Targeted Testing study of Toxcast Chemicals
    • Rats: Harlan Sprague-Dawley
    • Dose: not provided; 5 rats.