National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m010044

Testing Status of Pubertal vinclozolin study - M010044

 

CASRN: 50471-44-8

Formula: C12-H9-Cl2-NO3

Synonyms/Common Names

  • Vinclozolin pubertal study

Known Uses

fungicide, bactericide, wood preservative; used on fruits, vegetables, ornamental plants and vines.

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Comet Assay  (F75748B)  Completed 
    • Mice
  • Micronucleus  (F75748)  Completed 
    • Mice: B6C3F1
    • Male Negative 
  • Salmonella  (A31261)  Completed 
    •  Negative 

Organ Systems Toxicity

  • PND 23 to 53 Continuous Breeding (Legacy) (Gavage)  (RACB20104)  Completed 
    • Citation: Pubertal Toxicity Study of Vinclozolin, Flutamide and Phenobarbital in Male Sprague Dawley Rats and Methyxychlor, Ethinyl Estradiol and Phenobarbital in Female Sprague Dawley Rats when Administered in Corn Oil by Oral Gavage
    • Male Rats: Sprague Dawley
    • Dose: 0, 10, 30, OR 100 MG/KG/DAY.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.