National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m010052

Testing Status of Aloe-emodin - M010052

 

CASRN: 481-72-1

Formula: C15-H10-O5

Synonyms/Common Names

  • 9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)- (9CI)
  • Anthraquinone, 1,8-dihydroxy-3-hydroxymethyl-
  • 3-Hydroxymethylchrysazin
  • Rhabarberone

Known Uses

Recognized as a therapeutic dermatologic agent; extracts incorporated in a variety of topical health care products and cosmetics

Chemical Properties

Toxicity Effects (HSDB)

Long-Term Carcinogenicity

  • 40 weeks (Topical Application)  (C20116F)  Report Complete 
    • TR-553 (NIH Number: 10-5894)  (Peer Review Approval 02/27/2008A )
      Photococarcinogenesis Study of Aloe Vera [CASRN 481-72-1 (Aloe-emodin)] in SKH-1 Mice (Simulated Solar Light and Topical Application Study)
    • Mice: SKH-1 Hairless
    • Dose: 0, 3%, or 6% compound in cream with simulated solar light exposure.
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