National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m010062

Testing Status of Diphenolic acid - M010062

 

CASRN: 126-00-1

Formula: C17-H18-O4

Synonyms/Common Names

  • Benzenebutanoic acid, 4-hydroxy-gamma-(4-hydroxyphenyl)-gamma-methyl-(9CI)
  • 4,4-Bis(4-hydroxyphenyl)valeric acid (8CI)

Known Uses

Chemical intermediate in paint, lubricating oil additives, cosmetics, surfactants, plasticizers, and textile chemicals.

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Genetic Toxicology

  • Micronucleus  (A47664)  Completed 
    • Citation: Witt KL, Livanos E, Kissling GE, Torous DK, Caspary W, Tice RR, Recio L. Comparison of flow cytometry- and microscopy-based methods for measuring micronucleated reticulocyte frequencies in rodents treated with nongenotoxic and genotoxic chemicals. Mutat Res. 2008 Jan 8;649(1-2):101-13. Epub 2007 Aug 11.
    • Mice: B6C3F1
    • Male Negative 
  • Micronucleus  (F47664)  Completed 
    • Citation: Witt KL, Livanos E, Kissling GE, Torous DK, Caspary W, Tice RR, Recio L. Comparison of flow cytometry- and microscopy-based methods for measuring micronucleated reticulocyte frequencies in rodents treated with nongenotoxic and genotoxic chemicals. Mutat Res. 2008 Jan 8;649(1-2):101-13. Epub 2007 Aug 11.
    • Mice: B6C3F1
    • Male Negative 
    • Female NA 
  • Salmonella  (A00825)  Completed 
    •  Negative 
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