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Testing Status of 2,2',4,4',5,5'-Hexabromodiphenyl ether (PBDE 153) M010078


CASRN: 68631-49-2

Formula: C12-H4-Br6-O

Synonyms/Common Names

  • BDE 153
  • BR 33N
  • 1,1',Oxybis[2,4,5-Tribromobenzene (9Ci)
  • PBDE 153

Known Uses

Class of additive flame retardants used since the 1960s in thermoplastics to suppress or delay combustion.

Chemical Properties

Toxicity Effects (HSDB)

Special Studies

  • Absorption Disposition Metabolism Elimination (Gavage)  (S0895)  Completed 
    • Citation: Sanders JM, Lebetkin EH, Chen LJ, Burka LT. Disposition of 2,2',4,4',5,5'-hexabromodiphenyl ether (BDE153) and its interaction with other polybrominated diphenyl ethers (PBDEs) in rodents. Xenobiotica. 2006 Sep;36(9):824-37.Pubmed Abstract
    • Male and Female Rats: F344/N; Male and Female Mice: B6C3F1
    • Dose: From 0.1 to 100 umol/kg.

Genetic Toxicology

  • Salmonella  (A07760)  Completed 
    •  Negative