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Testing Status of Nevirapine M020003

 

CASRN: 129618-40-2

Formula: C15-H14-N4-O

Synonyms/Common Names

  • 6H-Dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one, 11-cyclopropyl-5,11-dihydro-4-methyl-
  • Nevirapine (AIDS)
  • NVP
  • Viramune

Known Uses

Drug for treatment of AIDS

Chemical Properties

Toxicity Effects (HSDB)

Genetic Toxicology

  • Salmonella  (G02003)  Completed 
    •  Negative 

Organ Systems Toxicity

  • 28 days Immunotoxicity (Gavage)  (IMM20304)  Completed 
    • Female Mice: B6C3F1
    • Dose: 0, 88, 176, or 266 mg/kg/day.
  • 28 days Immunotoxicity (Gavage)  (IMM20305)  Completed 
    • Female Mice: B6C3F1
    • Dose: 0, 88, 176, or 266 mg/kg/day.