National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m020004

Testing Status of Nelfinavir mesylate - M020004

 

CASRN: 159989-65-8

Formula: C32-H45-N3-O4-S.C-H4-O3-S

Synonyms/Common Names

  • Nelfinavir mesylate (AIDS)
  • NFLR
  • NFV
  • NFV

Known Uses

A potent HIV protease inhibitor, used as in combination with other antiviral drugs in the treatment of HIV in both adults and children

Chemical Properties

Toxicity Effects (HSDB)

Organ Systems Toxicity

  • 28 days Immunotoxicity (Gavage)  (IMM20604)  Completed 
    • Female Mice: B6C3F1
    • Dose: 0, 336, 672, or 1008.
  • 28 days Immunotoxicity (Gavage)  (IMM20711)  Completed 
    • Female Mice: B6C3F1
    • Dose: 0, 336, 672, or 1008.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.