National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m020016

Testing Status of TEF transgenics (TCDD) - M020016

 

CASRN: 1746-01-6

Formula: C12-H4-Cl4-O2

Synonyms/Common Names

  • TCDD (TEF transgenics)
  • TEF Transgenics (2,3,7,8-Tetrachlorodibenzo-p-dioxin)

Known Uses

Special evaluation of relative potency factors for papilloma induction by dioxin-like compounds in transgenic Tg.AC mice

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 26 weeks (Topical Application)  (C20201A)  Subchronic Toxicology Review 
    • Mice: Tg.AC (FVB/N) Hemizygous
    • Dose: FEMALE MICE: 0, 121 OR 760 NG/KG; 20/GROUP; 3X/WEEK.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.