National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m020019

Testing Status of TEF transgenics (PECDF) - M020019

 

CASRN: 57117-31-4

Formula: C12-H3-Cl5-O

Synonyms/Common Names

  • PECDF (TEF transgenics)
  • TEF Transgenics (2,3,4,7,8-Pentachlorodibenzofuran)

Known Uses

Special evaluation of relative potency factors for papilloma induction by dioxin-like compounds in transgenic Tg.AC mice

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 26 weeks (Topical Application)  (C20201C)  Subchronic Toxicology Review 
    • Mice: Tg.AC (FVB/N) Hemizygous
    • Dose: FEMALE MICE: 0, 72, 242, 720, OR 1520 NG/KG; 20/GROUP; 3X WEEK.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.