National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m020046

Testing Status of Pubertal phenobarbital study - M020046

 

CASRN: 50-06-6

Formula: C12-H12-N2-O3

Synonyms/Common Names

  • Phenobarbital pubertal study

Known Uses

Anticonvulsant, hypnotic, sedative

Chemical Properties

Toxicity Effects (HSDB)

Organ Systems Toxicity

  • males: PND 23-53/54 (approximately 30 days duration of exposure) and females: PND 22-42/43 (approximately 20 days duration of exposure) Continuous Breeding (Legacy) (Gavage)  (RACB20203)  Completed 
    • Citation: Pubertal Toxicity Study of Vinclozolin, Flutamide and Phenobarbital in Male Sprague Dawley Rats and Methyxychlor, Ethinyl Estradiol and Phenobarbital in Female Sprague Dawley Rats when Administered in Corn Oil by Oral Gavage
    • Male and Female Rats: Sprague Dawley
    • Dose: 0, 25, 50, OR 100 MG/KG/DAY.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.