National Toxicology Program

Testing Status of Glucosamine - M030010

CASRN: 3416-24-8

Formula: C6-H13-N-O5

Synonyms/Common Names

• 2-Amino-2-deoxy-d-glucose
• Chitosamine

Known Uses

Dietary supplement; ingredient in skin conditioners. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Short-Term Toxicity

• 13 weeks (Gavage)  (C20319B)  Completed 
  • Rats: Zucker - Lean (HsdHlr:ZUCKER-Lepr+); Rats: Zucker - Obese (HsdHlr:ZUCKER-Leprfa)
  • Dose: Male rats: 0, 30, 120, 300, or 600 mg/kg/bw/day; 12/dose lean and obese.