National Toxicology Program

Testing Status of Cedarwood oil - M030012

CASRN: 8000-27-9

Synonyms/Common Names

• Cedar oil

Known Uses

Ingredient in insect repellants; used as a fragrance in household items and cosmetics; immersion oils in microscopy

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Short-Term Toxicity

• 90 days (Topical Application)  (C20316)  Completed 
  • TOX-86 (NIH Number: 17-5944)
    NTP Technical Report on the Toxicity Studies of Cedarwood Oil (CASRN 8000-27-9) Cedarwood Oil (Virginia) Administered Dermally to F344/N Rats and B6C3F1/N Mice
  • Rats: F344/N; Mice: B6C3F1
  • Dose: R&M: 0, 6.25, 12.5, 25, 50, or 100 2 ml/kg rats and 0.5 ml/kg mice; 5X/week.

Genetic Toxicology

• Micronucleus  (A16009)  Completed 
  • Mice: B6C3F1
  • Male Negative 
  • Female Negative 
• Salmonella  (A51043)  Completed 
  •  Negative