National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m040032

Testing Status of NCT/DERT standardization experiment (APAP & AMAP) - M040032

 

CASRN: NCTSTANDARD

Synonyms/Common Names

  • APAP & AMAP (NCT/DERT standardization experiment)
  • NCT/DERT standardization experiment (Acetaminophen)
  • NCT/DERT standardization experiment (N-Acetyl-m-aminophenol)
  • Toxicogenomics standardization experiment

Known Uses

Standardization experiment for the toxicogenomics research consortium (TRC) using APAP and AMAP

Short-Term Toxicity

  • 1 day (Gavage)  (C20404)  Completed 
    • Mice: C57BL/6J (Jackson)
    • Dose: MM: 0 OR 300 MG/KG; SINGLE DOSE AT 6, 12, OR 24 HOURS -- 5 PER GROUP; CORE 5 PER GROUP; PROTHROMBIN TIME 5 PER GROUP.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.