National Toxicology Program

National Toxicology Program

Testing Status of Perfluorohexanoic acid (PFHXA) - M040048


CASRN: 307-24-4

Formula: C6-H-F11-O2

Synonyms/Common Names

  • C6 Carboxylic acid
  • Hexanoic acid, undecafluoro-

Known Uses

Breakdown product of stain- and grease-proof coatings on food packaging and household products.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 28 days (Gavage)  (C20613)  Histopath in progress 
    • Rats: Harlan Sprague-Dawley
    • Dose: M&F: 0, 31.3, 62.5, 125, 250, or 500 mg/kg/2x day.

Special Studies

  • (K04048)  Completed 

    Genetic Toxicology

    • Micronucleus  (G04048)  Completed 
      • Rats: Harlan Sprague-Dawley
      • Male Equivocal 
      • Female Negative 
    • Salmonella  (A97455)  Completed 
      •  Negative 

    Organ Systems Toxicity

    • Selected (R04048)  
      NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.