National Toxicology Program

National Toxicology Program

Testing Status of QT drugs (Loratadine) - M040077


CASRN: 79794-75-5

Formula: C22-H23-Cl-N2-O2

Synonyms/Common Names

  • Loratidine (QT drugs)

Known Uses

Antihistaminic; anti-allergic; antipruritic agent

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 1 day (Per os (Capsule))  (C20538C)  Completed 
    • Dog: Beagles
    • Dose: 0, 0.125, 0.25, 0.5, 1, 10, OR 20 MG/KG; 6/GROUP.
  • 13-Week (Per os (Capsule))  (C20538C)  Completed 
    • Dog: Beagles
    • Dose: TBD; 6/GROUP.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.