Testing Status of Metal Working Fluids: CIMSTAR 3800 M040094

 

CASRN: CIMSTAR3800

Synonyms/Common Names

  • Cimstar 3800 (metal working fluids)

Known Uses

Semisynthetic; metalworking fluid

Short-Term Toxicity

  • 13 weeks (Inhalation)  (C20515)  Completed 
    • Rats: F344/NTac; Mice: B6C3F1/N
    • Dose: R&M: 0, 25, 50, 100, 200, or 400 mg/m3; R: 20/sex/dose; M: 10/sex/dose.

Long-Term Carcinogenicity

  • 2 years (Inhalation)  (C20515)  Completed 
    • TR-586 (NIH Number: 15-5928)  (Peer Review Approval 05/22/2014A )
      Toxicology and Carcinogenesis Studies of CIMSTAR® 3800 (CASRN CIMSTAR3800) in Wistar Han Rats and B6C3F1 Mice (Inhalation Studies)
    • Rats: Wistar Han; Mice: B6C3F1/N
    • Carcinogenesis Results
      • Male Rats Equivocal Evidence 
      • Female Rats Equivocal Evidence 
      • Male Mice No Evidence 
      • Female Mice Some Evidence 
    • Dose: R&M: 0, 10, 30, or 100 mg/m3; 50/sex/species/dose.

Genetic Toxicology

  • Micronucleus  (A06575)  On Test 
    • Micronucleus  (A64536)  On Test 
      • Micronucleus  (F06575)  Completed 
        • Mice: B6C3F1
        • Male Negative 
        • Female Negative 
      • Micronucleus  (F64536)  Completed 
        • Rats: F344/NTac
        • Male Negative 
        • Female Negative 
      • Salmonella  (A69652)  Completed 
        •  Weakly Positive