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Testing Status of Metal working fluids (Trim SC210) M040095



Synonyms/Common Names

  • Trim SC210 (metal working fluids)

Known Uses

Semisynthetic; metalworking fluid

Short-Term Toxicity

  • 13 weeks (Inhalation)  (C20516)  Completed 
    • Citation: Ryan KR, Cesta MF, Herbert R, Brix A, Cora M, Witt K, Kissling G, Morgan DL. Comparative pulmonary toxicity of inhaled metalworking fluids in rats and mice. Toxicol Ind Health. 2016 Jun
    • Rats: F344/NTac; Mice: B6C3F1
    • Dose: R&M: 0, 25, 50, 100, 200, or 400 mg/m3; R: 20/sex/dose; M: 10/sex/dose.

Genetic Toxicology

  • Micronucleus  (F07614)  Completed 
    • Rats: Fischer 344
    • Male Equivocal 
    • Female Equivocal 
  • Micronucleus  (F26791)  Completed 
    • Mice: B6C3F1
    • Male Negative 
    • Female Negative 
  • Salmonella  (A22108)  Completed 
    •  Positive