National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m050071

Testing Status of N-Nitrosodimethylamine (TGMX rat liver evaluation) - M050071

 

CASRN: 62-75-9

Formula: C2-H6-N2-O

Synonyms/Common Names

  • Dimethylamine, N-nitroso-
  • TGMX rat liver evaluation (N-Nitrosodimethylamine)

Known Uses

Toxicogenomic evaluation of rat liver carcinogens and non-carcinogens. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 3 day & 2 weeks (Dosed-Water)  (C20540D)  Assigned 
    • Rats: F344/NTac
    • Dose: MALES ONLY: 0 OR 5 PPM.
  • 13 weeks & 8 weeks (Dosed-Water)  (C20540D)  Completed 
    • Rats: F344/NTac
    • Dose: MALES ONLY: 0 OR 5 PPM.
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