Testing Status of Emtricitabine (FTC) M060018
- Emtricitabine (AIDS)
Nucleoside antiretroviral AIDS drug used to treat HIV infection
- Preliminary Toxicokinetic Study (Gavage)
- Female Mice: CD-1 Reg.[Crl:CD1(ICR)]
- Dose: 12.5, 25 and 50 mg/kg.
- Comet Assay (CO)
- Citation: Hobbs CA, Recio L, Shepard K, Baldetti C, Winters J, Caspary, W, Witt KL. Abstract, presented at the EMS Annual Meeting in Atlanta GA, October 20-24, 2007. Gender-Specific Genotoxicity in Mice Treated with Emtricitabine and Tenofovir as Assessed by the Flow Cytometry Micronucleus and Comet Assays.
- Mice: B6C3F1
- Male Positive
- Female Positive