National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m060105

Testing Status of QT drugs (diltiazem hydrochloride) - M060105

 

CASRN: 33286-22-5

Formula: C22-H26-N2-O4-S.Cl-H

Synonyms/Common Names

  • Diltiazem hydrochloride (QT drugs)

Known Uses

Coronary vasodilator

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 1 day (Per os (Capsule))  (C20538B)  Completed 
    • Dog: Beagles
    • Dose: 0, 0.25, 0.5, 1, 2, 4, or 8 mg/kg; 6/group.
  • 13-Week (Per os (Capsule))  (C20538B)  Completed 
    • Dog: Beagles
    • Dose: 0, 0.25, 1, 2, 4, or 8 mg/kg; 6/group.
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