National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m060106

Testing Status of QT drugs (sotalol hydrochloride) - M060106

 

CASRN: 959-24-0

Formula: C12-H20-N2-O3-S.Cl-H

Synonyms/Common Names

  • 4'-(1-Hydroxy-2-(isopropylamino)ethyl)methanesulfonanilide monohydrochloride
  • Sotalol hydrochloride (QT drugs)

Known Uses

Drug; anti-adrenergic (beta-receptor)

Chemical Properties

Toxicity Effects (HSDB)

Short-Term Toxicity

  • 1 day (Per os (Capsule))  (C20538E)  Completed 
    • Dog: Beagles
    • Dose: 0, 0.5, 1, 2, 4, OR 8 MG/KG; 6/GROUP.
  • 13-Week (Per os (Capsule))  (C20538E)  Completed 
    • Dog: Beagles
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