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Testing Status of Zinc Carbonate, Basic M070002

 

CASRN: 5263-02-5

Formula: C2-H6-O12-Zn5

Synonyms/Common Names

  • Bis(carbonato)hexahydroxypentazinc
  • Dietary zinc
  • Zinc carbonate, basic
  • Zinc subcarbonate

Known Uses

Antiseptic (topical); astringent; dietary supplement.

Chemical Properties

Toxicity Effects (HSDB)

Long-Term Carcinogenicity

  • 2 years (Dosed-Feed)  (C20403)  Report in Preparation 
    • Study of dietary zinc in rats
    • TR-592   (Peer Review Approval 07/13/2017A )
      Toxicology and Carcinogenesis Study of Dietary Zinc (CASRN 5263-02-5) in Sprague Dawley Rats (Hsd:Sprague Dawley SD) (Feed Studies)
    • Rats: Harlan Sprague-Dawley
    • Carcinogenesis Results
      • Male Rats Equivocal Evidence EQUIVOCAL EVIDENCE WITH A DIET DEFICIENT IN ZINC (3.5 AND 7 PPM)
      • Female Rats No Evidence NO EVIDENCE WITH A DIET DEFICIENT IN ZINC (3.5 AND 7 PPM)
    • EQUIVOCAL EVIDENCE WITH A DIET DEFICIENT IN ZINC (3.5 AND 7 PPM)
    • Dose: R: 3.5, 7, 38 (control), 250, or 500 ppm zinc; 60/sex/group.

Genetic Toxicology

  • Comet Assay  (G07002F)  On Test 
    • Rats: Harlan Sprague-Dawley
  • Micronucleus  (C00048)  Completed 
    • Rats
  • Micronucleus  (G07002B)  Completed 
    • Rats: Harlan Sprague-Dawley
    • Male Negative 
    • Female Negative 
  • Micronucleus  (G07002)  Completed 
    • Rats: Harlan Sprague-Dawley
    • Male Negative 
    • Female Negative 
  • Micronucleus  (G07002D)  Completed 
    • Rats: Harlan Sprague-Dawley
    • Male Negative 
    • Female Negative 
  • Micronucleus  (G07002E)  Completed 
    • Rats: Harlan Sprague-Dawley
    • Male Negative 
    • Female Negative