Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of Insertional mutagenesis (LTR/SIN vectors) M070034

 

CASRN: INSERTMUT

Known Uses

Insertional mutagenesis studies using vector exposures

Short-Term Toxicity

  • 12 weeks (Intravenous)  (C20703)  Completed 
    • Mice: B6.SJL-Ptprc[a] Pepc[b]/BoyJ
    • Dose: Female mice/LTR vector (PRSF91.EGFP.PRE*): radiated 10 GY; 50k cells LTR; female mice/SIN vector (PSERS11.SF.EGFP.PRE*): radiated 10 GY; 50k cells SIN; female mice/controls: radiated 10 GY; empty vector cells; 15/group.