National Toxicology Program

National Toxicology Program
http://ntp.niehs.nih.gov/go/ts-m200021

Testing Status of Methylamine - M200021

 

CASRN: 74-89-5

Formula: C-H5-N

Synonyms/Common Names

  • Aminomethane
  • Carbinamine
  • Methanamine (9CI)
  • Monomethylamine

Known Uses

Intermediate in the manufacture of pharmaceuticals, pesticides, explosives, surfactants, and accelerators. Commonly used in the tanning and dyeing industries and as a fuel additive. Used as a polymerization inhibitor, a component of paint removers. Naturally occurring in food. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.

Chemical Properties

Toxicity Effects (HSDB)

Nomination Background

Genetic Toxicology

  • Mouse Lymphoma  (631545)  Completed 
    • Citation: Caspary, W., and Myhr, B. Mutagenicity of MIC and its reaction products to cultured mammalian cells. Mutation Res. Vol. 174 (1986) 285-293
    • Mice
    •  Positive 
  • Salmonella  (406286)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Negative 
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